The expiration date of a drug is estimated using stability testing under good manufacturing practices as determined by the Food and Drug Administration (FDA).
Similarly, medications should not be left in a hot car. American Society of Health System Pharmacists (ASHP.org). Medications remain most stable in dry, cool spaces away from light. Stability profiles of drug products extended beyond labeled expiration dates. The expiration date is the final day that the manufacturer guarantees the full potency and safety of a medication. pharmaceutical manufacturers are required by law to place expiration dates on prescription products prior to marketing.Drug expiration dates exist on most medication labels, including prescription, over-the-counter (OTC) and dietary (herbal) supplements. For legal and liability reasons, manufacturers will not make recommendations about the stability of drugs past the original expiration date.Insulin is used to control blood sugar in diabetes and may be susceptible to degradation after its expiration date.
Oral nitroglycerin (NTG), a medication used for angina (chest pain), may lose its potency quickly once the medication bottle is opened. Based on stability data, expiration dates on 88 percent of the lots were extended beyond their original expiration date for an average of 66 months.Of these 2652 lots, only 18 percent were terminated due to failure.These results suggest that many drug products may have extended shelf lives beyond their expiration date.However, it is difficult for any one consumer or health care provider to know which product could have an extended shelf life.Loss of potency can be a major health concern, especially when treating an infection with an antibiotic.